{"id":1154,"date":"2015-08-08T07:59:52","date_gmt":"2015-08-08T07:59:52","guid":{"rendered":"http:\/\/www.ahmadfanaei.com\/en\/?post_type=post&p=1154"},"modified":"2015-08-08T07:59:52","modified_gmt":"2015-08-08T07:59:52","slug":"gallbladder-polyps-cholecystectomy","status":"publish","type":"post","link":"https:\/\/ahmadfanaei.com\/en\/gallbladder-polyps-cholecystectomy\/","title":{"rendered":"Is cholecystectomy a reasonable treatment option for simple gallbladder polyps larger than \u06f1\u06f0 mm?"},"content":{"rendered":"

Polypoid lesions of the gallbladder are becoming an increasingly common incidental finding. It is very important to distinguish between a benign polyp and a malignant polyp because of the poor prognosis of gallbladder (GB) cancer, but the radiologic tools such as abdominal ultrasound (US) and computed tomography (CT) are not sufficient to distinguish between a benign polyp and a malignant polyp. Therefore, many researchers have attempted to identify the factors that can help in preoperative differentiation between a benign polyp and a malignant polyp.
\nGall bladder polyp (GBP) is a well-known pre-malignant lesion. The size of GBP, patient\u2019s age and presence of symptoms are the risk factors for GB cancer. GBPs of 10 to 12 mm in diameter have lower risk of malignancy compared to that in GBPs larger than 13 mm, which is similar to the risk of malignancy in GBPs smaller than 10 mm. The use of this surgical indication (GBPs larger than 13 mm GBP) can prevent 50% of unnecessary cholecystectomies without the risk of missing malignant GBPs. Our findings suggest that GBPs with a diameter of 10 to 12 mm in patients younger than 45 years of age old can be observed carefully.
\nAlthough the natural history of gallbladder polyps (GBPs) is not completely understood and most of the available studies are retrospective in nature, the well-known predictor of malignancy in GBPs is a size greater than 10 mm in diameter. However, when we applied the 10-mm size criterion for performing surgery, many polyps were found to be benign in a clinical setting. Most of the benign polyps had a size of 10 or 11 mm, and the incidence of these polyps is increasing as general medical examination is being universalized. Previous studies have shown that polyp size of more than 10 mm is associated with higher risk of developing malignancy; however so far, none of the studies have tried to differentiate between polyps of more than 10 mm in size for determining the incidence of malignancy.
\nTherefore, we analyzed the pathologically proven GBPs after cholecystectomy for 16 years at Samsung Medical Center to determine the relevance of the 10-mm size criterion.<\/p>\n

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